Shauna Christine Somerville

Carnegie Institution of Washington,
Department of Plant Biology,
260 Panama Street, Stanford,
CA 94305, U.S.A.
Email: Shauna@andrew2.stanford.edu
Web URL: http://www_ciwdpb.stanford.edu/research/research_ssomerville.php

Education:

• B.Sc. First Class Honors (Genetics), 1976, University of Alberta
• M.Sc. (Plant Breeding), 1978, University of Alberta
• Thesis: Evaluation of Harvesting Methodology and Maturity Assessments in Wheat and Barley. Advisor: K. Briggs
• Ph.D. (Agronomy/Plant Physiology), 1981, University of Illinois
• Thesis: A Mutant of Arabidopsis thaliana Deficient in Chloroplast Dicarboxylate Transport Activity. Advisor: W. Ogren

Employment:

• Visiting Assistant Professor, Department of Genetics, University of Alberta, 1981-1982.
• Research Associate, DOE Plant Research Laboratory, Michigan State University, 1982-1984.
• Research Assistant Professor, DOE Plant Research Laboratory, Michigan State University, 1984-1985.
• Assistant Professor, DOE Plant Research Laboratory and Botany and Plant Pathology Department, Michigan State University, January, 1986-1991.
• Associate Professor, DOE Plant Research Laboratory and Botany and Plant Pathology Department, Michigan State University, 1991-1993.
• Staff Scientist, Carnegie Institution of Washington, Department of Plant Biology, 1994-present.
• Adjunct Associate Professor, Department of Biological Sciences, Stanford University, 1994-2002
• Adjunct Professor, Department of Biological Sciences, Stanford University, 2002-present

Public Service (1997-present):

• Panel Member, Plant Biology Panel, N.S.F. (1995-1997)
• Advisory Board to the Functional Genomics Program for Soybean (1999-2002).
• Editorial Board of Genome Biology (1999-present)
• Advisory Board for the Arabidopsis Biological Resource Center (1999-2002)
• Advisory Board to the program Structure and Function of the Cotton Genome (2000-present)
• Advisory Panel for GenomeBC (2000)
• Associate Editor for Molecular Plant-Microbe Interactions (2001-present)
• Member of the Scientific Advisory Board for the Boyce Thompson Institute (June 2001)
• Organizer of “Functional Genomics” session at the annual Arabidopsis meeting (June 2001)
• Risø Fellow for Risø National Laboratory, Denmark (2002-2007)
• Advisory Board for the Functional Genomics of Roots Program (2002-2006)
• Collaborator and Advisor for the Functional Genomics of Grape Diseases Program in Chile (PI: Dr. P. Arce-Johnson, Catholic University, Santiago, Chile) (2002-2006)
• Advisory Board for Design and Analysis of Microarray Gene Expression Studies in Plants: Toward Sound Statistical Procedures (2002-2004)
• Editorial Advisor for Molecular Plant Pathology (2002-present)
• Participant in a DOE Workshop on Plant Systems Biology (Jan. 19, 2003)
• Review panel member N.I.H. Genetics Panel (Feb. 2003)
• Ad Hoc reviewer for the journals Genome, Genome Biology, Genomics, Molecular Plant-Microbe Interactions, Mycologia, Physiological and Molecular Plant Pathology, Plant Cell, Plant Journal, Plant Physiology, Plant Molecular Biology, Plant Science, Proceedings of the National Academy of Sciences, U.S.A., Science, Trends in Plant Science, Transgenic Research
• Ad Hoc reviewer for grant panels of the National Science Foundation, U.S. Department of Agriculture, U.S. Department of Energy, Iowa State University - Office of Biotechnology Grants Program, West Virginia University Senate Research Grants Program, U.S.-Israel Binational Agricultural Research and Development Fund, Netherlands Organization for Scientific Research, Swiss National Science Foundation, U.K. Biotechnology and Biological Sciences Research Council, M.J. Murdock Charitable Trust

Teaching Experience (1994-present):

• Plant Biology (BIO340 or BIO257), Stanford, University, Spring 1994-present, with Plant Biology Faculty
• Freshmen Seminar, Plant Genetic Engineering (BIO018N), Stanford University, Winter 1998, 1999, 2002 with C. Somerville

Bibliography (1997-present):

1. Giese, H., S. Hippe-Sanwald, S. Somerville, and J. Weller. 1997. Erysiphe graminis. In: Mycota, Vol. V, Part B: Plant Relationships (G.C. Carroll, and P. Tudzynski, eds.), Springer-Verlag, Berlin, pp. 55-78.
2. Somerville, S.C., and C.R. Somerville. 1996. Arabidopsis at 7: Still growing like a weed. The Plant Cell 8:1917-1933.
3. Buell, C.R., and S.C. Somerville. 1997. Use of Arabidopsis recombinant inbred lines reveals a monogenic and a novel digenic resistance mechanism to Xanthomonas campestris pv campestris. The Plant Journal 12: 21-29
4. Botella, M.A., M.J. Coleman, D.E. Hughes, M.T. Nishimura, J.D.G. Jones, and S.C. Somerville. 1997. Map positions of 47 Arabidopsis sequences with sequence similarity to disease resistance genes. The Plant Journal 12: 1197-1211.
5. Wilson, I., J. Vogel, and S. Somerville. 1997. Signalling pathways: A common theme in plants and animals? Current Biology 7, R175-R178.
6. Somerville, S.C., M. Nishimura, D. Hughes, I. Wilson, and J. Vogel. 1998. Alternate methods of gene discovery -- the candidate gene approach and DNA microarrays. Pages 297-309 in: Cellular Integration of Signaling Pathways in Plant Development. NATO ASI Series, Vol. H104 (F. Lo Schiavo, R.L. Last, G. Morelli and N.V. Raikhel, eds.). Springer-Verlag, Berlin.
7. Kehoe, D., P. Villand, and S. Somerville. 1999. DNA microarrays for studies of higher plants and other photosynthetic organisms. Trends in Plant Sciences 4: 38-41.
8. Adam, L., S. Ellwood, I. Wilson, S. Xiao, G. Saenz, R. Oliver, J.G. Turner, and S. Somerville. 1999. Comparison of Erysiphe cichoracearum and E. cruciferarum and a survey of 360 Arabidopsis thaliana accessions for resistance to these two powdery mildew pathogens. Molecular Plant-Microbe Interactions 12:1031-1043.
9. Somerville, C.R. and S.C. Somerville. 1999. Functional genomics of plants. Science 285: 380-383.
10. Richmond, T., and S. Somerville. 2000. Chasing the dream: Plant EST microarrays. Current Opinion in Plant Biology 3: 108-116.
11. Vogel, J., and S.C. Somerville. 2000. Isolation and characterization of powdery mildew resistant Arabidopsis mutants. Proceedings of the National Academy of Sciences, USA 97: 1897-1902.
12. Schenk, P.M., K. Kazan, I. Wilson, J.P. Anderson, T. Richmond, S.C. Somerville, and J.M. Manners. 2000. Coordinated plant defense responses in Arabidopsis revealed by microarray analysis. Proceedings of the National Academy of Sciences, USA 97: 11655-11660.
13. Wilson, I.W., and S.C. Somerville. 2000. Isolation and characterization of disease resistance genes in Arabidopsis. In: Plant-Microbe Interactions, Vol. 3 (G. Stacey and N.T. Keen, eds.), Chapman and Hall, New York. pp. 141-180.
14. Zhou, F., J. Kurth, F.S. Wei, C. Elliot, G. Vale, N. Yahiaoui, B. Keller, S. Somerville, R. Wise and P. Schulze-Lefert. 2001. Cell-autonomous expression of barley Mla1 confers race-specific resistance to the powdery mildew fungus via a Rar1-independent signaling. Plant Cell13: 337-350.
15. Wilson, I.W., C.L. Schiff, D.E. Hughes and S.C. Somerville. 2001. Quantitative trait loci analysis of powdery mildew disease resistance in the Arabidopsis thaliana accession Kashmir-1. Genetics 158: 1301-1309.
16. Schiff, C.L., I.W. Wilson and S.C. Somerville. 2001. Polygenic powdery mildew disease resistance in Arabidopsis thaliana. Quantitative trait analysis of the accession Warschau-1. Plant Pathology 50: 690-701.
17. Vogel, J. and S.C. Somerville. Powdery mildew of Arabidopsis: A model system for host-parasite interactions. In: The Powdery Mildews: A Comprehensive Treatise (R. Bélanger, R. Dik and W.R. Bushnell, eds.), American Phytopathological Society Press, St. Paul, MN. pp. 161-168.
18. Finkelstein, D., R. Ewing, J. Gollub, F. Sterky, S. Somerville and J.M. Cherry. 2000. Iterative linear regression by sector. Presentation at CAMDA ‘00 Conference on the Critical Assessment of Techniques for Microarray Data Analysis, December 18-19, 2000, Duke, N.C.
19. Wu, S.-H., K. Ramonell, J. Gollub and S. Somerville. 2001 Plant gene expression profiling with DNA microarrays. Plant Physiology and Biochemistry 39: 917-926.
20. Finkelstein, D., R. Ewing, J. Gollub, F. Sterky, J.M. Cherry and S. Somerville. 2002. Microarray data quality analysis: lessons from the AFGC project. Plant Molecular Biology 48: 119-131.
21. Ramonell, K.M., B. Zhang, R.M. Ewing, Y. Chen, D.Xu, G. Stacey and S. Somerville. 2002. Microarray analysis of chitin elicitation in Arabidopsis thaliana. Molecular Plant Pathology 3: 301-311.
22. Ramonell, K.M. and S. Somerville. 2002. The genomics parade of pathogen responses: To infinity and beyond. Current Opinion in Plant Biology 5: 291-294.
23. Vogel, J.P., T.K. Raab, C. Schiff and S. Somerville. 2002. PMR6, a pectate-lyase like gene required for powdery mildew susceptibility in Arabidopsis. Plant Cell 14: 2095-2106.
24. Nishimura, M. and S. Somerville. 2002. Resisting attack. Science 295: 2032-2033.
25. Childs, G., J. DeRisi, T. harris, A Holloway, B.-H. Hou, A. Massimi, M. Murphy and S. Somerville. 2002. Printing spotted glass microarrays. In: DNA Microarrays: A Molecular Cloning Manual (D. Botwell and J. Sambrook, eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. pp. 61-100.
26. Bittner, M., R. Butow, J. DeRisi, M. Diehn, J. Eberwine, C.B. Epstein, R. Glynne, S. Grimmond, T. Ideker, J.E. Kacharmina, S. Katsabanis, J. Khan, J. Lee, C.L. Liu, P. Marciano, F.M. Marincola, T. McIntosh, D. Monte, J.R. Pollack, V. Rhodius, S. Somerville, E. Tom, E. Wang, J.S. Wei, D. Wilhite, and S. Ybarra. 2002. Expression analysis of RNA. In: DNA Microarrays: A Molecular Cloning Manual (D. Botwell and J. Sambrook, eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. pp. 101-288.
27. Zhang, B., K. Ramonell, S. Somerville and G. Stacey. Characterization of early, chitin-induced gene expression in Arabidopsis. Molecular Plant-Microbe Interactions 15: 963-970.
28. Jackson, R.B., C.R. Linder, M. Lynch, M. Purugganan, S. Somerville and S. Thayer. Linking molecular insight and ecological research. Trends in Ecology and Evolution 17: 409-414.
29. Stein, M. and S.C. Somerville. MLO, a novel regulator of plant defenses and cell death, binds calmodulin. Trends in Plant Science 7: 379-380.
30. Klok, E.J., I. Wilson, D. Wilson, S.C. Chapman, R.M. Ewing, R. Dolferus, W.J. Peacock, S.C. Somerville and E.S. Dennis. 2002. Expression profile analysis of the low oxygen response in Arabidopsis root cultures. Plant Cell 14: 2181-2494.
    

Additional papers stemming from the S.C.S. Laboratory (underlined authors)

1. Alfenito, M.R., E. Souer, C.D. Goodman, R. Buell, J. Mol, R. Koes and V. Walbot. 1998. Functional complementation of anthocyanin sequestration in the vacuole by widely divergent glutathione S-transferases. Plant Cell 10: 1135_1149.
2. Schulze-Lefert, P. and J. Vogel. 2000. Closing the ranks to attack by powdery mildew. Trends in Plant Sciences 5: 343-348.
3. Kloek, A.P., M.L. Verbsky, S.B. Sharma, J.E. Schoelz, J. Vogel, D.F. Klessig and B.N. Kunkel. 2001. Resistance to Pseudomonas syringae conferred by an Arabidopsis thaliana coronatine-insensitive (coi1) mutation occurs through two distinct mechanisms. Plant Journal 26: 509-522.

(2003/01/31)